Wednesday, September 19, 2007

Coffee now under attack

Well, is coffee the next target?

In a recent Finish study, and using questionnaires with 24,000 patients and observing them prospectively for 13.2 years, investigators determined daily coffee consumption increased their risk of having to use medication for blood pressure.

The study showed at baseline subjects were aged 25 to 64 years and had no history of antihypertensive drug treatment, coronary heart disease, or stroke. Multivariate adjustments were then made for age, sex, study year, education, leisure-time physical activity, smoking status, body mass index (BMI), high total cholesterol level, history of diabetes, and consumption of alcohol, tea, fruit, vegetable, sausage, and bread.

The investigators stated the results indicated that coffee drinking seems to increase the risk of antihypertensive drug treatment, and this risk was higher in subjects with low-to-moderate coffee intakes; however, there was no significantly increased trend in drinkers of ~ 1 cup or ≥ 8 cups/day.

The increased risk showed no dose-response relation, but a threshold was observed between those who drank > 1 cup/day and those who drank only 0-1 cups/d.

In my opinion, this study was limited by self-reported data on coffee intake, potential bias from a possible change in coffee consumption during follow-up, lack of data on consumption of cola beverages and chocolate, but most importantly, they do not mention doing multivariate adjustments for family history.

We typically tell patients that 90% of Hypertension is genetic and hereditary and therefore, not including this in the study is a major flaw reducing the believability.

Don’t eliminate your coffee, but moderation continues to be the prevailing thought.

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1 Comments:

Anonymous Anonymous said...

I COULD GIVE UP ALOT OF THINGS, BUT NOT MY COFFEE!!!

9/19/2007 09:41:00 PM  

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